Weasels Rip My Flesh (1979)
Returning from the planet Venus, an errant NASA spacecraft crashes into the ocean, spilling its radioactive cargo. Enveloped by a radioactive mass, a rabid weasel is transformed into a gigantic killer mutant. Prowling the countryside, the huge weasel kills and devours victims. The creature is captured by a disturbed scientist who plans to use its regenerative blood to amass an army of similar monsters, enabling him to conquer the Earth.
What makes this movie different from other 70s horror films is that it's actually a super-8 movie by a 16-year old that somehow got released on DVD.
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tsarstepan commented
Killer paper mache weasels need love too.
https://www.youtube.com/watch?v=_4Q59-Y4GbQ